Extragonadal retroperitoneal germ cell tumor: primary versus metastases?

Extragonadal retroperitoneal germ cell tumor: primary versus metastases?

OBJECTIVE Primary extragonadal germ cell tumors are rare and their histogenetic origin is not clear. We describe two cases presenting as primary retroperitoneal germ cell tumors without clinical evidence of testicular tumor. METHODS A 21 and 18 years-old patients presented retroperitoneal choriocarcinoma and yolk sac tumor, respectively. In both cases, testicular palpation was not suspicious ...

Retroperitoneal Extragonadal Nonseminomatous Germ Cell Tumor with Synchronous Orbital Metastasis

A huge retroperitoneal tumor with a right orbital mass was detected and proved to be an extragonadal nonseminomatous germ cell tumor on biopsy. BEP chemotherapy caused some regression in orbital mass however no change in retroperitoneal tumor size as well as serum tumor marker levels occurred. Herein, we present a rarely seen entity of extragonadal retroperitoneal nonseminomatous germ cell tumo...

Primary Extragonadal Retroperitoneal Pure Yolk Sac Tumor

Primary germ cell tumors of extragonadal origin are rare and exact incidence of this type cancer is unknown. They have been estimated to represent 3-5% of all adult germ cell malignancies (1). The origin of primary extragonadal germ cell tumors (EGGCT) is still a matter of debate. According to widely accepted theory, during embryogenesis, germ cells are misplaced anywhere at the midline. The me...

Is orchiectomy always necessary in retroperitoneal extragonadal germ cell tumours?

Extragonadal retroperitoneal germ cell tumor: evidence of origin in the testis.

BACKGROUND The origin of extragonadal retroperitoneal germ cell tumors remains controversial. Whether they develop primarily in the retroperitoneum or whether they are metastases of a primary testicular tumor has long been debated. PATIENTS AND METHODS We retrospectively analyzed 26 patients treated as having primary extragonadal retroperitoneal germ cell tumors based upon the findings of tes...